Colorimetric and Photocurrent-Polarity-Switching Photoelectrochemical Dual-Mode Sensing Platform for Highly Selective Detection of Mercury Ions Based on the Split G-Quadruplex-Hemin Complex.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c03084
Abstract: Mercury ion (Hg2+) is one of the most harmful heavy metal ions with the greatest impact on public health. Herein, based on the excellent catalytic activity toward 3,3',5,5'-tetramethylbenzidine (TMB) and the strong photocurrent-polarity-switching ability to… read more here.
Keywords: split quadruplex; detection; quadruplex hemin; hemin ... See more keywords
An intermolecular-split G-quadruplex DNAzyme sensor for dengue virus detection
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DOI: 10.1039/d0ra05439a
Abstract: Nucleic acids have special ability to organize themselves into various non-canonical structures, including a four-stranded DNA structure termed G-quadruplex (G4) that has been utilized for diagnostic and therapeutic applications. Herein, we report the ability of… read more here.
Keywords: dengue virus; split quadruplex; detection; dnazyme ... See more keywords
Split G-quadruplex-programmed label-free CRISPR-Cas12a sensing system.
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DOI: 10.1039/d3cc01239e
Abstract: A split G-quadruplex (G4)-programmed Cas12a platform was established, validated, and optimized. The split G4 motif was recruited as substrate for Cas12a, and the label-free sensing platform provided a concentration-dependent response towards the input target. Furthermore,… read more here.
Keywords: programmed label; label free; split quadruplex; cas12a ... See more keywords
Exploration of intramolecular split G-quadruplex and its analytical applications
Sign Up to like & getrecommendations! Published in 2019 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkz749
Abstract: Abstract Distinct from intermolecular split G-quadruplex (Inter-SG), intramolecular split G-quadruplex (Intra-SG) which could be generated in a DNA spacer-inserted G-quadruplex strand has not been systematically explored. Not only is it essential for the purpose of… read more here.
Keywords: exploration intramolecular; analytical applications; intramolecular split; split quadruplex ... See more keywords