LAMSA: fast split read alignment with long approximate matches
Sign Up to like & getrecommendations! Published in 2017 at "Bioinformatics"
DOI: 10.1093/bioinformatics/btw594
Abstract: Motivation: Read length is continuously increasing with the development of novel high-throughput sequencing technologies, which has enormous potentials on cutting-edge genomic studies. However, longer reads could more frequently span the breakpoints of structural variants (SVs)… read more here.
Keywords: split read; approximate matches; split; read alignment ... See more keywords
SIGAR: Inferring Features of Genome Architecture and DNA Rearrangements by Split-Read Mapping
Sign Up to like & getrecommendations! Published in 2020 at "Genome Biology and Evolution"
DOI: 10.1093/gbe/evaa147
Abstract: Abstract Ciliates are microbial eukaryotes with distinct somatic and germline genomes. Postzygotic development involves extensive remodeling of the germline genome to form somatic chromosomes. Ciliates therefore offer a valuable model for studying the architecture and… read more here.
Keywords: sigar; germline genome; dna; split read ... See more keywords