Improved Split TEV GPCR β-arrestin-2 Recruitment Assays via Systematic Analysis of Signal Peptide and β-arrestin Binding Motif Variants
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DOI: 10.3390/bios13010048
Abstract: G protein-coupled receptors (GPCRs) are major disease-relevant drug targets; robust monitoring of their activities upon drug treatment is key to drug discovery. The split TEV cell-based assay technique monitors the interaction of an activated GPCR… read more here.
Keywords: gpcr arrestin; split tev; arrestin recruitment; tev ... See more keywords