Centriole splitting caused by loss of the centrosomal linker protein C-NAP1 reduces centriolar satellite density and impedes centrosome amplification
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Biology of the Cell"
DOI: 10.1091/mbc.e16-05-0325
Abstract: Knockout of the centriolar linker C-NAP1 increased centriole separation and dispersed centriolar satellites. Primary cilia formed normally, even though the ciliary rootlet was mislocalized, and mechanosensory ciliary signaling was intact. Reduced levels of centrosome amplification… read more here.
Keywords: splitting caused; centrosome amplification; linker; centriole splitting ... See more keywords