R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors
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DOI: 10.7554/elife.53895
Abstract: During kidney development, WNT/β-catenin signalling has to be tightly controlled to ensure proliferation and differentiation of nephron progenitor cells. Here, we show in mice that the signalling molecules RSPO1 and RSPO3 act in a functionally… read more here.
Keywords: differentiation; nephron progenitors; nephron; spondin signalling ... See more keywords