Articles with "sponge alkaloid" as a keyword



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A cytotoxic survey on 2‐amino‐1H‐imidazol based synthetic marine sponge alkaloid analogues

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Published in 2022 at "Drug Development Research"

DOI: 10.1002/ddr.22006

Abstract: Here, we describe the synthesis and biologic activity evaluation of 20 novel synthetic marine sponge alkaloid analogues with 2‐amino‐1H‐imidazol (2‐AI) core. Cytotoxicity was tested on murine 4T1 breast cancer, A549 human lung cancer, and HL‐60… read more here.

Keywords: alkaloid analogues; marine sponge; cancer; sponge alkaloid ... See more keywords