Two new pyrrolo-2-aminoimidazoles from a Myanmarese marine sponge, Clathria prolifera
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Natural Medicines"
DOI: 10.1007/s11418-018-1205-y
Abstract: Marine organisms such as marine sponges and soft corals are valuable sources of pharmacologically active secondary metabolites. In our ongoing research on the discovery of new secondary metabolites from marine organisms, two new pyrrolo-2-aminoimidazoles, clathriroles… read more here.
Keywords: sponge; two new; pyrrolo aminoimidazoles; sponge clathria ... See more keywords
Procerolides A-B from Microcionidae marine sponge Clathria procera: Anti-inflammatory macrocylic lactones with selective cyclooxygenase-2 attenuation properties.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.104663
Abstract: Cyclooxygenase-2 has been recognized to catalyze the formation of inflammatory prostaglandins from arachidonic acid. Attenuation potential against cyclooxygenase-2 coupled with greater anti-inflammatory selectivity index were contemplated to be vital indicators to assess anti-inflammatory activities of… read more here.
Keywords: anti inflammatory; cyclooxygenase; attenuation; marine sponge ... See more keywords
Cyclic Cystine-Bridged Peptides from the Marine Sponge Clathria basilana Induce Apoptosis in Tumor Cells and Depolarize the Bacterial Cytoplasmic Membrane.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.7b00477
Abstract: Investigation of the sponge Clathria basilana collected in Indonesia afforded five new peptides, including microcionamides C (1) and D (2), gombamides B (4), C (5), and D (6), and an unusual amide, (E)-2-amino-3-methyl-N-styrylbutanamide (7), along… read more here.
Keywords: cyclic cystine; clathria basilana; cystine bridged; sponge clathria ... See more keywords
New Crambescidin-Type Alkaloids from the Indonesian Marine Sponge Clathria bulbotoxa
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DOI: 10.3390/md16030084
Abstract: A crude methanolic extract of the Indonesian sponge Clathria bulbotoxa showed a potent cytotoxic activity against the human epidermoid carcinoma A431 cells. An investigation of the active components led to the isolation of three new… read more here.
Keywords: new crambescidin; clathria bulbotoxa; crambescidin type; activity ... See more keywords