CircRNA circPDSS1 promotes the gastric cancer progression by sponging miR‐186‐5p and modulating NEK2
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.27714
Abstract: The aim of this study is to investigate the regulatory mechanism of circPDSS1/miR‐186‐5p/NEK2 axis on the viability and proliferation in gastric cancer (GC) cell line. Differentially expressed circRNAs, miRNAs, and mRNAs in GC tissues and… read more here.
Keywords: 186 nek2; gastric cancer; sponging mir; circpdss1 ... See more keywords
circ_0008797 attenuates non-small cell lung cancer proliferation, metastasis, and aerobic glycolysis by sponging miR-301a-3p/SOCS2.
Sign Up to like & getrecommendations! Published in 2022 at "Environmental toxicology"
DOI: 10.1002/tox.23518
Abstract: PURPOSE This paper firstly reported the exact function of circ_0008797 on non-small cell lung cancer (NSCLC) progression. METHODS NSCLC tissues/matched normal tissues were harvested from 88 NSCLC patients. RNA fluorescence in situ hybridization experiment was… read more here.
Keywords: lung; circ; mir 301a; nsclc cells ... See more keywords
CircZNF609 is involved in the pathogenesis of focal segmental glomerulosclerosis by sponging miR-615-5p.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.07.066
Abstract: As a set of distinct syndromes, focal segmental glomerulosclerosis (FSGS) is the most common cause of adult nephrotic syndrome with diverse mechanisms. We recently found that expression of the circular RNA circZNF609 is increased in… read more here.
Keywords: focal segmental; sponging mir; segmental glomerulosclerosis; circznf609 ... See more keywords
Circular RNA Arhgap12 modulates doxorubicin-induced cardiotoxicity by sponging miR-135a-5p.
Sign Up to like & getrecommendations! Published in 2020 at "Life sciences"
DOI: 10.1016/j.lfs.2020.118788
Abstract: AIM This study aimed to investigate the regulatory role of differentially-expressed circular RNAs (circRNAs) in mouse cardiomyocytes during doxorubicin (DOX)-induced cardiotoxicity. MAIN METHODS Two groups of mice were injected with equal volumes (0.1 mL) of normal… read more here.
Keywords: dox induced; induced cardiotoxicity; sponging mir; cardiotoxicity ... See more keywords
CircNFIX promotes progression of pituitary adenoma via CCNB1 by sponging miR-34a -5p
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and Cellular Endocrinology"
DOI: 10.1016/j.mce.2020.111140
Abstract: Previous studies have shown that CCNB1 affects the invasiveness of pituitary adenomas, and it is of great significance to find the upstream mechanism of regulating CCNB1.In this study, we explored a significantly overexpressed circRNA in… read more here.
Keywords: sponging mir; mir 34a; circnfix; pituitary adenomas ... See more keywords
Long non-coding RNA metallothionein 1 pseudogene 3 promotes p2y12 expression by sponging miR-126 to activate platelet in diabetic animal model
Sign Up to like & getrecommendations! Published in 2019 at "Platelets"
DOI: 10.1080/09537104.2018.1457781
Abstract: Abstract Platelet hyperaggregation and hypercoagulation are associated with increase of thrombogenic risk, especially in patients with type 2 diabetes (T2D). High activity of P2Y12 receptor is found in T2D patients, exposing such patients to a… read more here.
Keywords: expression sponging; mir 126; sponging mir; p2y12 expression ... See more keywords
Linc01133 promotes proliferation and metastasis of human renal cell carcinoma through sponging miR-760
Sign Up to like & getrecommendations! Published in 2022 at "Cell Cycle"
DOI: 10.1080/15384101.2022.2054250
Abstract: ABSTRACT Renal cell carcinoma (RCC) is one of the most frequent human tumors and has brought great threats to the health of the people around the globe. It was reported that linc01133, a long non-coding… read more here.
Keywords: cell; cell carcinoma; renal cell; linc01133 ... See more keywords
lncRNA H19 promotes glioblastoma multiforme development by activating autophagy by sponging miR-491-5p
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2022.2065947
Abstract: ABSTRACT Glioblastoma multiforme (GBM) is a malignant cancer with severely poor survival, and the cells continue to thrive during hypoxia and toxic stress through autophagy. To validate the oncogenic role of long noncoding RNA H19… read more here.
Keywords: sponging mir; mir 491; h19; glioblastoma multiforme ... See more keywords
Ceramide synthase 6 antisense RNA 1 contributes to the progression of breast cancer by sponging miR-16-5p to upregulate ubiquitin-conjugating enzyme E2C
Sign Up to like & getrecommendations! Published in 2022 at "Anti-Cancer Drugs"
DOI: 10.1097/cad.0000000000001381
Abstract: Breast cancer (BC) is the most dangerous female mortality all over the world, described by unavoidable spread and metastaticity of BC cells. Increasing evidences verified that lncRNA play a major role in the tumorgenesis and… read more here.
Keywords: sponging mir; as1; cers6 as1; as1 ube2c ... See more keywords
CircUSP34 accelerate osteosarcoma maliganant progression by sponging miR-16-5p.
Sign Up to like & getrecommendations! Published in 2021 at "Cancer science"
DOI: 10.1111/cas.15147
Abstract: Osteosarcoma (OS) is a primary and highly malignant mesenchymal tissue tumor. The specific pathological mechanism underlying disease initiation or progression remains unclear. CircRNAs are a type of covalently circular RNA with a head-to-tail junction site.… read more here.
Keywords: proliferation migration; sponging mir; mir; circusp34 ... See more keywords
lncRNA NBAT1 Inhibits Cell Metastasis and Promotes Apoptosis in Endometrial Cancer by Sponging miR-21-5p to Regulate PTEN
Sign Up to like & getrecommendations! Published in 2022 at "Computational and Mathematical Methods in Medicine"
DOI: 10.1155/2022/9304392
Abstract: Objective Long noncoding RNA neuroblastoma-associated transcript 1 (NBAT1) is implicated in the progression of various cancers. Nevertheless, its biological function in endometrial cancer (EC) remains unknown. Methods The levels of NBAT1, miR-21-5p, and PTEN in… read more here.
Keywords: metastasis; endometrial cancer; nbat1 inhibits; sponging mir ... See more keywords