Astrocytic mitochondria in adult mouse brain slices show spontaneous calcium influx events with unique properties.
Sign Up to like & getrecommendations! Published in 2021 at "Cell calcium"
DOI: 10.1016/j.ceca.2021.102383
Abstract: Astrocytes govern critical aspects of brain function via spontaneous calcium signals in their soma and processes. A significant proportion of these spontaneous astrocytic calcium events are associated with mitochondria, however, the extent, sources, or kinetics… read more here.
Keywords: adult mouse; spontaneous calcium; astrocytic mitochondria; calcium ... See more keywords
Spontaneous calcium waves in the developing enteric nervous system
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.316
Abstract: Loss-of-function mutations in PYCR2 cause hypomyelinating leukodystrophy 10 (HLD10) (MIM: 616420) characterized by postnatal degenerative microcephaly, severely delayed psychomotor development, and hypomyelination. Here, we report 3 additional patients with a novel germline homozygous missense G249V,… read more here.
Keywords: mouse brain; spontaneous calcium; waves developing; brain ... See more keywords
Cadinane Sesquiterpenoids and Their Glycosides from Alangium chinense That Inhibit Spontaneous Calcium Oscillations.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of natural products"
DOI: 10.1021/acs.jnatprod.1c00978
Abstract: Nine new cadinane sesquiterpenoids, alanenses A-I (1-9), were isolated from the leaves of Alangium chinense together with three previously reported analogues (10-12). The structures of these molecules were elucidated by interpretation of spectroscopic and spectrometric… read more here.
Keywords: inhibit spontaneous; cadinane sesquiterpenoids; alangium chinense; sesquiterpenoids glycosides ... See more keywords
Stochastic spontaneous calcium release events and sodium channelopathies promote ventricular arrhythmias
Sign Up to like & getrecommendations! Published in 2017 at "Chaos"
DOI: 10.1063/1.4999612
Abstract: Premature ventricular complexes (PVCs), the first initiating beats of a variety of cardiac arrhythmias, have been associated with spontaneous calcium release (SCR) events at the cell level. However, the mechanisms underlying the degeneration of such… read more here.
Keywords: ventricular arrhythmias; scr mediated; spontaneous calcium; calcium release ... See more keywords
Impact of R-Carvedilol on β2-Adrenergic Receptor-Mediated Spontaneous Calcium Release in Human Atrial Myocytes
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10071759
Abstract: A hallmark of atrial fibrillation is an excess of spontaneous calcium release events, which can be mimicked by β1- or β2-adrenergic stimulation. Because β1-adrenergic receptor blockers (β1-blockers) are primarily used in clinical practice, we here… read more here.
Keywords: calcium; calcium release; spontaneous calcium; adrenergic receptor ... See more keywords
Nitric Oxide Synthase Blockade Impairs Spontaneous Calcium Activity in Mouse Primary Hippocampal Culture Cells
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24032608
Abstract: Oscillation of intracellular calcium concentration is a stable phenomenon that affects cellular function throughout the lifetime of both electrically excitable and non-excitable cells. Nitric oxide, a gaseous secondary messenger and the product of nitric oxide… read more here.
Keywords: calcium; nitric oxide; spontaneous calcium; oxide synthase ... See more keywords