Functional changes of the SCN in spontaneous hypertension but not after the induction of hypertension
Sign Up to like & getrecommendations! Published in 2018 at "Chronobiology International"
DOI: 10.1080/07420528.2018.1469035
Abstract: ABSTRACT The present study investigates the circadian behavior of spontaneously hypertensive rats (SHRs) during the pre-hypertensive and hypertensive stage, with the aim to gain insight into whether observed changes in the functionality of suprachiasmatic nucleus… read more here.
Keywords: period; functional changes; spontaneous hypertension; induction hypertension ... See more keywords
Blood-Brain Barrier Disruption and Perivascular Beta-Amyloid Accumulation in the Brain of Aged Rats with Spontaneous Hypertension: Evaluation with Dynamic Contrast-Enhanced Magnetic Resonance Imaging
Sign Up to like & getrecommendations! Published in 2018 at "Korean Journal of Radiology"
DOI: 10.3348/kjr.2018.19.3.498
Abstract: Objective Whether blood-brain barrier (BBB) disruption induced by chronic spontaneous hypertension is associated with beta-amyloid (Aβ) accumulation in the brain remains poorly understood. The purpose of this study was to investigate the relationship between BBB… read more here.
Keywords: hippocampus cortex; accumulation; disruption; accumulation brain ... See more keywords
Trimethylamine N-oxide promotes demyelination in spontaneous hypertension rats through enhancing pyroptosis of oligodendrocytes
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.963876
Abstract: Background Hypertension is a leading risk factor for cerebral small vessel disease (CSVD), a brain microvessels dysfunction accompanied by white matter lesions (WML). Trimethylamine N-oxide (TMAO), a metabolite of intestinal flora, is correlated with cardiovascular… read more here.
Keywords: hypertension rats; hypertension; pyroptosis; trimethylamine oxide ... See more keywords