Spontaneous seizure and partial lethality of juvenile Shank3-overexpressing mice in C57BL/6 J background
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DOI: 10.1186/s13041-018-0403-6
Abstract: The SH3 and multiple ankyrin repeat domains 3 (SHANK3) gene encodes core scaffolds in neuronal excitatory postsynapses. SHANK3 duplications have been identified in patients with hyperkinetic disorders and early-onset generalized tonic-clonic seizures. Consistently, Shank3 transgenic… read more here.
Keywords: seizure partial; spontaneous seizure; shank3 mice; shank3 ... See more keywords