Articles with "spontaneously hypertensive" as a keyword



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Processing method modulates the effectiveness of black beans for lowering blood cholesterol in spontaneously hypertensive rats.

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Published in 2020 at "Journal of the science of food and agriculture"

DOI: 10.1002/jsfa.10654

Abstract: BACKGROUND Various foods are known to have beneficial effects on health when consumed whole, however, there is a trend to prepare foods from processed ingredients, and it remains unclear whether the benefits of the whole… read more here.

Keywords: black beans; spontaneously hypertensive; hypertensive rats; method ... See more keywords
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N‐methyl‐d‐aspartate receptor dysfunction in the prefrontal cortex of stroke‐prone spontaneously hypertensive rat/Ezo as a rat model of attention deficit/hyperactivity disorder

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Published in 2018 at "Neuropsychopharmacology Reports"

DOI: 10.1002/npr2.12007

Abstract: We previously reported that stroke‐prone spontaneously hypertensive rat/Ezo (SHRSP/Ezo) has high validity as an attention deficit/hyperactivity disorder (AD/HD) animal model, based on its behavioral phenotypes, such as inattention, hyperactivity, and impulsivity. Fronto‐cortical dysfunction is implicated… read more here.

Keywords: stroke prone; spontaneously hypertensive; hyperactivity; hypertensive rat ... See more keywords
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Pregnancy improves cognitive deficit and neuronal morphology atrophy in the prefrontal cortex and hippocampus of aging spontaneously hypertensive rats

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Published in 2017 at "Synapse"

DOI: 10.1002/syn.21991

Abstract: It is well known that the survival is higher in women compared to men and women have a better survival prognosis than men in some pathologies such as vascular dementia (VD). Our previous reports showed… read more here.

Keywords: spontaneously hypertensive; pregnancy improves; atrophy; months old ... See more keywords
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Antihypertensive effects of Korean wild simulated ginseng (Sanyangsam) extracts in spontaneously hypertensive rats

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Published in 2019 at "Food Science and Biotechnology"

DOI: 10.1007/s10068-019-00617-5

Abstract: Ginseng possesses a wide spectrum of medicinal effects and has widely been used in traditional medicine for thousands of years. In this study, the antihypertensive effect of Korean wild simulated ginseng in spontaneously hypertensive rats… read more here.

Keywords: spontaneously hypertensive; ginseng; hypertensive rats; wild simulated ... See more keywords
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Protective effects of losartan on some type 2 diabetes mellitus-induced complications in Wistar and spontaneously hypertensive rats

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Published in 2020 at "Metabolic Brain Disease"

DOI: 10.1007/s11011-020-00534-1

Abstract: Diabetes mellitus type 2 (T2DM) is characterized by resistance of insulin receptors and/or inadequate insulin secretion resulting in metabolic and structural complications including vascular diseases, arterial hypertension and different behavioral alterations. We aimed to study… read more here.

Keywords: t2dm; spontaneously hypertensive; hypertensive rats; t2dm induced ... See more keywords
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Aerobic training-mediated DNA hypermethylation of Agtr1a and Mas1 genes ameliorate mesenteric arterial function in spontaneously hypertensive rats.

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Published in 2021 at "Molecular biology reports"

DOI: 10.1007/s11033-021-06929-2

Abstract: BACKGROUND The imbalance of vasoconstrictor and vasodilator axes of the renin-angiotensin system (RAS) is observed in hypertension. Exercise regulates RAS level and improves vascular function. This study focused on the contribution of RAS axes in… read more here.

Keywords: agtr1a mas1; spontaneously hypertensive; function; exercise ... See more keywords
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Ketogenic diet aggravates kidney dysfunction by exacerbating metabolic disorders and inhibiting autophagy in spontaneously hypertensive rats.

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Published in 2021 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2021.08.003

Abstract: AIMS To assess the effects of a ketogenic diet on metabolism and renal fibrosis in spontaneously hypertensive rats. MATERIALS AND METHODS Male spontaneously hypertensive rats (SHRs) and Wistar Kyoto (WKY) rats were randomly divided into… read more here.

Keywords: spontaneously hypertensive; hypertensive rats; renal autophagy; renal fibrosis ... See more keywords
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Adeno-associated virus-mediated in vivo suppression of expression of EPHX2 gene modulates the activity of paraventricular nucleus neurons in spontaneously hypertensive rats.

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Published in 2022 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2022.03.084

Abstract: BACKGROUND Hypertension can be attributed to increased sympathetic activities. Presympathetic neurons in the paraventricular nucleus (PVN) of the hypothalamus are capable of modulating sympathetic outflow, thus contributing to the pathogenesis of neurogenic hypertension. Epoxyeicosatrienoic acids… read more here.

Keywords: expression; paraventricular nucleus; eet; hypertensive rats ... See more keywords
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Static magnetic field on behavior, hematological parameters and organ damage in spontaneously hypertensive rats.

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Published in 2020 at "Ecotoxicology and environmental safety"

DOI: 10.1016/j.ecoenv.2020.111085

Abstract: Previous studies showed contradictory results of static magnetic field (SMF) influence on behavior, hematological parameters and organ damage. The aim of this study was to investigate influence of subchronic continuous exposure to upward and downward… read more here.

Keywords: oriented smf; spontaneously hypertensive; hypertensive rats; hematological parameters ... See more keywords
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Metformin reduces proteinuria in spontaneously hypertensive rats by activating the HIF-2α-VEGF-A pathway.

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Published in 2020 at "European journal of pharmacology"

DOI: 10.1016/j.ejphar.2020.173731

Abstract: Metformin has protective effects on diabetic nephropathy. However, the mechanism underlying the renoprotective action of metformin in spontaneously hypertensive rats (SHR) is not completely understood. We determined the role of metformin in proteinuria and investigated… read more here.

Keywords: spontaneously hypertensive; hypertensive rats; metformin; rat ... See more keywords
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Protective effect of calcitriol on podocytes in spontaneously hypertensive rat

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Published in 2018 at "Journal of the Chinese Medical Association"

DOI: 10.1016/j.jcma.2018.01.010

Abstract: Background: Hypertension is a major global public health issue. Uncontrolled hypertension leads to organ damage, especially renal damage. Calcitriol is used to treat osteoporosis, promote bone formation, and increase bone mass. Previous studies have demonstrated… read more here.

Keywords: spontaneously hypertensive; compared group; group; group compared ... See more keywords