A phospho-tyrosine–based signaling module using SPOP, CSK, and LYN controls TLR-induced IRF activity
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DOI: 10.1126/sciadv.abq0084
Abstract: Toll-like receptors (TLRs) recognize pathogen- and host-derived factors and control immune responses via the adaptor protein MyD88 and members of the interferon regulatory transcription factor (IRF) family. IRFs orchestrate key effector functions, including cytokine release,… read more here.
Keywords: csk; tlr induced; activity; spop csk ... See more keywords