Quantification of mutant SPOP proteins in prostate cancer using mass spectrometry-based targeted proteomics
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DOI: 10.1186/s12967-017-1276-7
Abstract: BackgroundSpeckle-type POZ protein (SPOP) is an E3 ubiquitin ligase adaptor protein that functions as a potential tumor suppressor, and SPOP mutations have been identified in ~10% of human prostate cancers. However, it remains unclear if… read more here.
Keywords: mutant spop; spop mutations; spop proteins; prostate cancer ... See more keywords