Cancer Mutations in SPOP Put a Stop to Its Inter-compartmental Hops.
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DOI: 10.1016/j.molcel.2018.09.025
Abstract: In this issue of Molecular Cell, Bouchard et al. (2018) identify liquid-liquid phase separation as a mechanism for substrate-triggered localization of SPOP and ubiquitination machinery to different nuclear bodies and describe how cancer mutations disrupt this… read more here.
Keywords: cancer mutations; mutations spop; put stop; spop put ... See more keywords