Snail promotes prostate cancer migration by facilitating SPOP ubiquitination and degradation.
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DOI: 10.1016/j.bbrc.2020.05.187
Abstract: Prostate cancer (PCa) is the second leading cause of cancer-associated mortality in men. Speckle-type pox virus and zinc finger protein (SPOP), the most frequently mutated gene in PCa, functions as a tumor suppressor via degradation… read more here.
Keywords: degradation; spop ubiquitination; prostate cancer; snail ... See more keywords