Plasma metals as potential biomarkers in dementia: a case–control study in patients with sporadic Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2018 at "Biometals"
DOI: 10.1007/s10534-018-0089-3
Abstract: Sporadic Alzheimer’s disease (AD) is a neurodegenerative disorder that causes the most prevalent form of age-related dementia but its pathogenesis remains obscure. Altered regulation of metals, particularly pan-cerebral copper deficiency, and more regionally-localized perturbation of… read more here.
Keywords: control study; alzheimer disease; control; sporadic alzheimer ... See more keywords
Modelling Sporadic Alzheimer’s Disease Using Induced Pluripotent Stem Cells
Sign Up to like & getrecommendations! Published in 2018 at "Neurochemical Research"
DOI: 10.1007/s11064-018-2663-z
Abstract: Developing cellular models of sporadic Alzheimer’s disease (sAD) is challenging due to the unknown initiator of disease onset and the slow disease progression that takes many years to develop in vivo. The use of human… read more here.
Keywords: alzheimer disease; sporadic alzheimer; disease; pluripotent stem ... See more keywords
Effects of tannic acid in streptozotocin-induced sporadic Alzheimer's Disease: insights into memory, redox status, Na+, K+-ATPase and acetylcholinesterase activity.
Sign Up to like & getrecommendations! Published in 2019 at "Archives of physiology and biochemistry"
DOI: 10.1080/13813455.2019.1673430
Abstract: The aim of this study was to investigate the ability of tannic acid (TA) in preventing memory deficits and neurochemical alterations observed in a model for Sporadic Dementia of Alzheimer's Type. Rats were treated with… read more here.
Keywords: tannic acid; sporadic alzheimer; acetylcholinesterase activity; activity ... See more keywords
Brain properties predict proximity to symptom onset in sporadic Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2018 at "Brain"
DOI: 10.1093/brain/awy093
Abstract: Estimated years to symptom onset (EYO) is a measurement developed to track disease progression in patients with genetic Alzheimer’s disease. Vogel et al. apply this concept to individuals with a parental history of sporadic Alzheimer’s… read more here.
Keywords: alzheimer disease; sporadic alzheimer; disease; brain properties ... See more keywords
Corrigendum to “Slower Dynamics and Aged Mitochondria in Sporadic Alzheimer's Disease”
Sign Up to like & getrecommendations! Published in 2021 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2021/1643631
Abstract: [This corrects the article DOI: 10.1155/2017/9302761.]. read more here.
Keywords: dynamics aged; aged mitochondria; sporadic alzheimer; corrigendum slower ... See more keywords
Neuroprotective Effect of Artichoke-Based Nanoformulation in Sporadic Alzheimer’s Disease Mouse Model: Focus on Antioxidant, Anti-Inflammatory, and Amyloidogenic Pathways
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15101202
Abstract: The vast socio-economic impact of Alzheimer’s disease (AD) has prompted the search for new neuroprotective agents with good tolerability and safety profile. With its outstanding role as antioxidant and anti-inflammatory, alongside its anti-acetylcholinesterase activity, the… read more here.
Keywords: sporadic alzheimer; antioxidant anti; alzheimer disease; anti inflammatory ... See more keywords
Altered O-GlcNAcylation and mitochondrial dysfunction, a molecular link between brain glucose dysregulation and sporadic Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2022 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.354515
Abstract: Alzheimer’s disease is a neurodegenerative disease that affected over 6.5 million people in the United States in 2021, with this number expected to double in the next 40 years without any sort of treatment. Due… read more here.
Keywords: sporadic alzheimer; disease; alzheimer disease; brain glucose ... See more keywords