Metabolome and transcriptome analysis on muscle of sporadic inclusion body myositis
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Clinical and Translational Neurology"
DOI: 10.1002/acn3.51657
Abstract: Sporadic inclusion body myositis (sIBM) is the most common acquired myopathy in patients older than 50 years of age. sIBM is hardly responds to any immunosuppressing theraphies, and its pathophysiology remains elusive. This study aims to… read more here.
Keywords: inclusion body; sporadic inclusion; body myositis; metabolome transcriptome ... See more keywords
Pathomechanisms of anti–cytosolic 5′‐nucleotidase 1A autoantibodies in sporadic inclusion body myositis
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Neurology"
DOI: 10.1002/ana.24919
Abstract: Sporadic inclusion body myositis (sIBM), an intractable progressive muscle disease, frequently occurs in older persons. sIBM pathogenesis may involve protein degradation dysfunction and immune abnormalities. Autoantibodies recognizing cytosolic 5′‐nucleotidase 1A (cN1A) were found in plasma… read more here.
Keywords: body myositis; cytosolic nucleotidase; sporadic inclusion; inclusion body ... See more keywords
Immunohistochemical and ultrastructural analysis of sporadic inclusion body myositis: a case series
Sign Up to like & getrecommendations! Published in 2018 at "Rheumatology International"
DOI: 10.1007/s00296-018-4221-z
Abstract: Sporadic inclusion body myositis (s-IBM) is a progressive, skeletal muscle disease with poor prognosis. However, establishing the final diagnosis is difficult because of the lack of clear biomarkers in the blood serum and very slow… read more here.
Keywords: sporadic inclusion; microscopy; immunohistochemical ultrastructural; rheumatology ... See more keywords
Mitochondrial DNA depletion in sporadic inclusion body myositis
Sign Up to like & getrecommendations! Published in 2019 at "Neuromuscular Disorders"
DOI: 10.1016/j.nmd.2019.02.001
Abstract: Sporadic inclusion body myositis (sIBM) is a late onset disorder of unkown aetiology. Mitochondrial changes such as cytochrome oxidase deficient fibres are a well recognised feature and mitochondrial DNA (mtDNA) deletions have also been reported,… read more here.
Keywords: sporadic inclusion; mtdna; body myositis; mitochondrial dna ... See more keywords
Diagnosis and Clinical Development of Sporadic Inclusion Body Myositis and Polymyositis With Mitochondrial Pathology: A Single-Center Retrospective Analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of neuropathology and experimental neurology"
DOI: 10.1093/jnen/nlab101
Abstract: To review our diagnostic and treatment approaches concerning sporadic inclusion body myositis (sIBM) and polymyositis with mitochondrial pathology (PM-Mito), we conducted a retrospective analysis of clinical and histological data of 32 patients diagnosed as sIBM… read more here.
Keywords: mitochondrial pathology; sporadic inclusion; pathology; body myositis ... See more keywords
Sporadic inclusion body myositis – a myodegenerative disease or an inflammatory myopathy
Sign Up to like & getrecommendations! Published in 2017 at "Neuropathology and Applied Neurobiology"
DOI: 10.1111/nan.12384
Abstract: Sporadic inclusion body myositis (sIBM) is an insidious late‐onset progressive myopathy that typically affects patients over the age of 50. Clinically, patients develop a characteristic pattern of weakness that affects the forearm flexors and knee… read more here.
Keywords: body myositis; sporadic inclusion; disease; inclusion body ... See more keywords
Reader response: Granulomatosis-associated myositis: High prevalence of sporadic inclusion body myositis
Sign Up to like & getrecommendations! Published in 2020 at "Neurology"
DOI: 10.1212/wnl.0000000000011068
Abstract: We read with great interest the recent article by Dr. Dieudonné et al.1 The authors reported the high prevalence of sporadic inclusion body myositis (SIBM) in patients with granulomatous myositis, and a significant proportion of… read more here.
Keywords: high prevalence; myositis; inclusion body; sporadic inclusion ... See more keywords
Mitochondrial dysfunction underlying sporadic inclusion body myositis is ameliorated by the mitochondrial homing drug MA-5
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0231064
Abstract: Sporadic inclusion body myositis (sIBM) is the most common idiopathic inflammatory myopathy, and several reports have suggested that mitochondrial abnormalities are involved in its etiology. We recruited 9 sIBM patients and found significant histological changes… read more here.
Keywords: sporadic inclusion; dysfunction; mitochondrial dysfunction; body myositis ... See more keywords
INCREASING DAILY DURATION OF REHABILITATION FOR INPATIENTS WITH SPORADIC INCLUSION BODY MYOSITIS MAY CONTRIBUTE TO IMPROVEMENT IN ACTIVITIES OF DAILY LIVING: A NATIONWIDE DATABASE COHORT STUDY
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Rehabilitation Medicine"
DOI: 10.2340/jrm.v55.5289
Abstract: Objective To analyse the association between the daily duration of rehabilitation for inpatients with sporadic inclusion body myositis and improvement in activities of daily living, using a Japanese nationwide inpatient administrative claims database. Methods Data… read more here.
Keywords: sporadic inclusion; rehabilitation; inclusion; inclusion body ... See more keywords
Sporadic Inclusion Body Myositis: A Clinicopathological Study
Sign Up to like & getrecommendations! Published in 2021 at "Neurology India"
DOI: 10.4103/0028-3886.319212
Abstract: Background: Sporadic inclusion body myositis (s-IBM) is rare in India. Aim: The aim of this study was to diagnose s-IBM according to the European Neuromuscular Center (ENMC) IBM research diagnostic criteria 2011. Materials and Methods:… read more here.
Keywords: body myositis; sporadic inclusion; study; inclusion body ... See more keywords