Spore‐displayed enzyme cascade with tunable stoichiometry
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DOI: 10.1002/btpr.2416
Abstract: Taking the advantages of inert and stable nature of endospores, we developed a biocatalysis platform for multiple enzyme immobilization on Bacillus subtilis spore surface. Among B. subtilis outer coat proteins, CotG mediated a high expression… read more here.
Keywords: spore surface; stoichiometry; enzyme cascade; spore displayed ... See more keywords
Human Plasminogen Exacerbates Clostridioides difficile Enteric Disease and Alters the Spore Surface.
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DOI: 10.1053/j.gastro.2020.06.032
Abstract: BACKGROUND & AIMS The protease plasmin is an important wound healing factor, but it is not clear how it affects gastrointestinal infection-mediated damage, such as that resulting from Clostridioides difficile. We investigated the role of… read more here.
Keywords: spore surface; clostridioides difficile; disease; plasmin ... See more keywords
CotG Mediates Spore Surface Permeability in Bacillus subtilis
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DOI: 10.1128/mbio.02760-22
Abstract: Bacterial spores are quiescent cells extremely resistant to a variety of unphysiological conditions, including the presence of lytic enzymes. Such resistance is also due to the limited permeability of the spore surface, which does not… read more here.
Keywords: cotg; lytic enzymes; bacillus subtilis; spore surface ... See more keywords