Sporotrichosis: The Emerging Fungal Threats to Animals
Sign Up to like & getrecommendations! Published in 2019 at "Fungal Biology"
DOI: 10.1007/978-3-030-18586-2_8
Abstract: Sporotrichosis is a chronic granulomatous mycotic infection caused by Sporothrix schenckii, the saprophytic dimorphic fungi frequently seen in cats, dogs, horses, camels, fowls, rats, mice, hamsters, chimpanzees and humans. Cats have the severe form of… read more here.
Keywords: sporotrichosis; sporotrichosis emerging; sporothrix schenckii; emerging fungal ... See more keywords
A rare case of disseminated Sporothrix schenckii with bone marrow involvement in a patient with idiopathic CD4 lymphocytopenia
Sign Up to like & getrecommendations! Published in 2017 at "IDCases"
DOI: 10.1016/j.idcr.2017.06.012
Abstract: Sporothrix schenckii is a pathogen with a predilection for dissemination in immunocompromised individuals, often with HIV. We report a case of disseminated sporotrichosis in an unfortunate 25 year old male (without HIV) who was originally… read more here.
Keywords: sporothrix schenckii; schenckii; patient; case disseminated ... See more keywords
Functional characterization of the Sporothrix schenckii Ktr4 and Ktr5, mannosyltransferases involved in the N-linked glycosylation pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Research in microbiology"
DOI: 10.1016/j.resmic.2018.02.004
Abstract: Sporothrix schenckii is one of the causative agents of the deep-seated mycosis sporotrichosis, a fungal infection with worldwide distribution. Fungus-specific molecules and biosynthetic pathways are potential targets for the development of new antifungal drugs. The… read more here.
Keywords: sporothrix schenckii; schenckii; linked glycans; family ... See more keywords
Sporothrix schenckii regulates macrophage inflammatory responses via the c-JUN-induced Dab2 transcription.
Sign Up to like & getrecommendations! Published in 2022 at "Experimental dermatology"
DOI: 10.1111/exd.14580
Abstract: Macrophages, which serve as a bridge between innate and adaptive immunity, play an important role in sporotrichosis. Sporothrix schenckii infections can produce immune responses such as macrophage polarization and inflammatory factor secretion. In the early… read more here.
Keywords: expression; sporothrix schenckii; jun; dab2 ... See more keywords
Identification of two potential inhibitors of Sporothrix brasiliensis and Sporothrix schenckii in the Pathogen Box collection
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0240658
Abstract: Sporotrichosis is a neglected endemic mycosis with a high incidence in Latin America, mainly in Brazil. Sporothrix schenckii is the most frequent species in Latin America, whereas Sporothrix brasiliensis is the predominant species observed in… read more here.
Keywords: brasiliensis; sporothrix brasiliensis; pathogen box; sporothrix schenckii ... See more keywords
Silencing of OCH1 unveils the role of Sporothrix schenckii N-linked glycans during the host–fungus interaction
Sign Up to like & getrecommendations! Published in 2019 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s185037
Abstract: Background Sporothrix schenckii is a neglected fungal pathogen for the human being and other mammals. In several fungal systems, Och1 is a Golgi α1,6-mannosyltransferase with a key function in the synthesis of N-linked glycans; which… read more here.
Keywords: host fungus; linked glycans; sporothrix schenckii; interaction ... See more keywords
Terpinen-4-ol inhibits the growth of Sporothrix schenckii complex and exhibits synergism with antifungal agents.
Sign Up to like & getrecommendations! Published in 2019 at "Future microbiology"
DOI: 10.2217/fmb-2019-0146
Abstract: Aim: This study investigated the effect of terpinen-4-ol against Sporothrix schenckii complex and its interactions with antifungals. Materials & methods: The antifungal activity of terpinen-4-ol was evaluated by broth microdilution. The potential effect on cellular… read more here.
Keywords: sporothrix schenckii; schenckii complex; inhibits growth; terpinen inhibits ... See more keywords
Virulence Factors of Sporothrix schenckii
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8030318
Abstract: Sporothrix schenckii is one of the etiological agents of sporotrichosis. In this review, we discuss the virulence factors that have been proven to participate in the S. schenckii-host interaction. Among these known factors, we can… read more here.
Keywords: sporotrichosis; virulence; virulence factors; factors sporothrix ... See more keywords
Keratinocyte Response to Infection with Sporothrix schenckii
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8050437
Abstract: Sporotrichosis is a subacute, or chronic mycosis caused by traumatic inoculation of material contaminated with the fungus Sporothrix schenckii which is part of the Sporothrix spp. complex. The infection is limited to the skin, although… read more here.
Keywords: sporothrix schenckii; infection; response infection; keratinocyte response ... See more keywords
The Search for Cryptic L-Rhamnosyltransferases on the Sporothrix schenckii Genome
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8050529
Abstract: The fungal cell wall is an attractive structure to look for new antifungal drug targets and for understanding the host-fungus interaction. Sporothrix schenckii is one of the main causative agents of both human and animal… read more here.
Keywords: schenckii genome; cryptic rhamnosyltransferases; search cryptic; sporothrix schenckii ... See more keywords
Silencing of ROT2, the Encoding Gene of the Endoplasmic Reticulum Glucosidase II, Affects the Cell Wall and the Sporothrix schenckii–Host Interaction
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Fungi"
DOI: 10.3390/jof8111220
Abstract: Sporothrix schenckii is a member of the Sporothrix pathogenic clade and one of the most common etiological agents of sporotrichosis, a subcutaneous fungal infection that affects both animal and human beings. Like other fungal pathogens,… read more here.
Keywords: interaction; cell wall; wall; sporothrix schenckii ... See more keywords