The Application of T.SPOT-TB Assay for Early Diagnosis of Active Tuberculosis in Chronic Kidney Disease Patients Receiving Immunosuppressive Treatment
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Investigative Surgery"
DOI: 10.1080/08941939.2019.1566417
Abstract: Abstract Background: The current study investigated the clinical application of the T-SPOT.TB assay for detecting tuberculosis (TB) infection in chronic kidney disease patients treated with immunosuppressive therapy. Methods: Clinical data from 91 patients were retrospectively… read more here.
Keywords: chronic kidney; application spot; spot; treatment ... See more keywords
Dried plasma spot assay for sunitinib and its active metabolite by high performance liquid chromatography tandem mass spectrometry: 547P
Sign Up to like & getrecommendations! Published in 2017 at "Annals of Oncology"
DOI: 10.1093/annonc/mdx678.004
Abstract: plasma protein-A (PAPP-A) is a metalloproteinase that cleaves insulin-like growth factor 1 (IGF-1) from a circulating complex formed with insulin-like growth factor binding protein 4 (IGFBP4). Increased bioavailability of IGF1 subsequently impacts on tumour biology.… read more here.
Keywords: active metabolite; dried plasma; sunitinib active; plasma spot ... See more keywords
Combination of Blood Routine Examination and T-SPOT.TB Assay for Distinguishing Between Active Tuberculosis and Latent Tuberculosis Infection
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2021.575650
Abstract: Background Distinguishing between active tuberculosis (ATB) and latent tuberculosis infection (LTBI) remains challenging. Methods Between 2013 and 2019, 2,059 (1,097 ATB and 962 LTBI) and another 883 (372 ATB and 511 LTBI) participants were recruited… read more here.
Keywords: atb; spot; model; tuberculosis ... See more keywords
Platelets correlate with false negative T-SPOT.TB results by inhibiting interferon-γ production in T cells via degranulation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.937416
Abstract: Background T-SPOT.TB (T-SPOT) is widely used for the detection of Mycobacterium tuberculosis infection by detecting interferon-gamma (IFN-γ) release in T lymphocytes. This assay is performed on peripheral blood mononuclear cells (PBMCs) separated by Ficoll density… read more here.
Keywords: spot; spot assay; iscs positive; production cells ... See more keywords
Clinical application of metagenomic next-generation sequencing in tuberculosis diagnosis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.984753
Abstract: Objective The purpose of this study was to evaluate the clinical diagnostic value of metagenomic next-generation sequencing (mNGS) for tuberculosis (TB). Methods This retrospective study included 52 patients with suspected TB infection. mNGS, targeted PCR,… read more here.
Keywords: spot assay; tuberculosis; rate; next generation ... See more keywords
Minimizing the variables of voiding spot assay for comparison between laboratories
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DOI: 10.7717/peerj.15420
Abstract: The voiding spot assay (VSA) is increasingly being adopted as a standard method for assessing mouse urinary function. However, VSA outcomes are highly sensitive to housing environment and procedural parameters. Many variables exist among laboratories,… read more here.
Keywords: spot assay; voiding spot; laboratories minimizing; vsa ... See more keywords