High-Throughput Top-Down Proteomic Analysis of Picogram-Level Complex Samples Using Multisegment Spray-Capillary CE-MS.
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DOI: 10.1021/acs.analchem.5c02334
Abstract: Ultrasensitive top-down proteomics techniques provide valuable insights into PTM-regulated cellular functions in mass-limited samples. Capillary electrophoresis (CE) is a promising separation technique for top-down proteomics due to its high resolution, high sensitivity, and short cycle… read more here.
Keywords: spray capillary; top proteomics; analysis; mass limited ... See more keywords