Effect of amino acids on the stability of spray freeze‐dried immunoglobulin G in sugar‐based matrices
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmaceutical Sciences"
DOI: 10.1016/j.ejps.2018.04.013
Abstract: ABSTRACT The purpose of this study was to prepare spray freeze‐dried particles of immunoglobulin G (IgG) using various combinations of trehalose and different amino acids (leucine, phenylalanine, arginine, cysteine, and glycine), and investigate the effect… read more here.
Keywords: spray freeze; stability; amino; amino acids ... See more keywords
Spray freeze drying as an alternative technique for lyophilization of polymeric and lipid-based nanoparticles.
Sign Up to like & getrecommendations! Published in 2017 at "International journal of pharmaceutics"
DOI: 10.1016/j.ijpharm.2016.11.023
Abstract: The use of nanoparticles for drug delivery is still restricted by their limited stability when stored in an aqueous medium. Freeze drying is the standard method for long-term storage of colloidal nanoparticles; however the method… read more here.
Keywords: technique; freeze drying; spray freeze; polymeric lipid ... See more keywords
Can spray freeze-drying improve the re-dispersion of crystalline nanoparticles of pure naproxen?
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DOI: 10.1016/j.ijpharm.2019.04.061
Abstract: Spray freeze drying (SFD) was used to prepare re-dispersible powders of crystalline, pure-drug nanodispersions of naproxen in lactose and stabilized with hydroxypropyl cellulose. The particle size of the rehydrated powders was determined using static light… read more here.
Keywords: freeze drying; spray; spray freeze; crystalline nanoparticles ... See more keywords
Spray freeze-dried monolithic silica aerogel based on water-glass with thermal superinsulating properties
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DOI: 10.1016/j.matlet.2018.07.035
Abstract: Abstract In this study, silica aerogels were prepared using water-glass precursor based on two drying strategies, namely conventional freeze drying (C-FD) and spray freeze drying (S-FD). It was known that the pore structure of silica… read more here.
Keywords: spray freeze; silica; silica aerogel; water glass ... See more keywords
Solid state stability of polyphenols from a plant extract after fluid bed atmospheric spray-freeze-drying
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DOI: 10.1016/j.powtec.2017.06.054
Abstract: Abstract Dry powder extracts are the most suitable pharmaceutical forms of phytomedicines due to their greater physical and chemical stability in the solid state, in addition to the possibility of easy preparation of tablets and… read more here.
Keywords: solid state; spray freeze; stability; bed atmospheric ... See more keywords
Bulk Dynamic Spray Freeze-Drying Part 2: Model-Based Parametric Study for Spray-Freezing Process Characterization.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2019.01.011
Abstract: Spray freeze-drying is an evolving technology that combines the benefits of spray-drying and conventional lyophilization techniques to produce drug substance and drug product as free-flowing powders. The high surface-to-volume ratio associated to the submillimeter spray-frozen… read more here.
Keywords: freeze drying; spray; spray freeze; spray freezing ... See more keywords