Loss of Spry1 attenuates vascular smooth muscle proliferation by impairing mitogen‐mediated changes in cell cycle regulatory circuits
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.26486
Abstract: Signals from growth factors or mechanical stimuli converge to promote vascular smooth muscle cell (VSMC) migration and proliferation, key events in the pathogenesis of intimal hyperplasia upon vascular injury. Spry1, a regulator of receptor tyrosine… read more here.
Keywords: loss spry1; spry1; cell cycle; proliferation ... See more keywords
Circ_0020093 ameliorates IL-1β-induced apoptosis and extracellular matrix degradation of human chondrocytes by upregulating SPRY1 via targeting miR-23b
Sign Up to like & getrecommendations! Published in 2021 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-021-04186-2
Abstract: Osteoarthritis (OA) is a chronic disease characterized by articular cartilage degeneration and uncontrolled chondrocyte apoptosis. At present, accumulating evidence introduces that circular RNA (circRNA) is involved in the development of OA. The aim of our… read more here.
Keywords: apoptosis; mir 23b; human chondrocytes; spry1 ... See more keywords
Abstract 4806: Spry1 as a potential new hypoxia modulator in cutaneous melanoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-4806
Abstract: Introduction: At present, the precise role of Spry proteins in tumor progression is still debated. Our previous study showed that Spry1 knockdown (Spry1KO) in BRAFV600-mutant cutaneous melanoma (CM) promoted cell cycle arrest and apoptosis, repressed… read more here.
Keywords: spry1 potential; hypoxia; angiogenesis; cutaneous melanoma ... See more keywords