Differences in the genomic profiles of cell‐free DNA between plasma, sputum, urine, and tumor tissue in advanced NSCLC
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DOI: 10.1002/cam4.1935
Abstract: Liquid biopsy has provided an efficient way for detection of gene alterations in advanced non‐small‐cell lung cancer (NSCLC). However, the correlation between systematic determination of somatic genomic alterations in liquid biopsy and tumor biopsy still… read more here.
Keywords: tumor tissue; plasma; sputum; liquid biopsy ... See more keywords
A GRIM fate for human neutrophils in airway disease
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DOI: 10.1002/jlb.5ce0418-162r
Abstract: Nowhere in biomedical research does a cell type seem as simultaneously vital and vexing as the neutrophil. Human immunity deteriorates rapidly in the absence of neutrophils whereas their dysfunctional abundance can cause misery and harm,… read more here.
Keywords: airway disease; sputum; drug; human neutrophils ... See more keywords
Effectiveness of inhaled hypertonic saline application for sputum induction to improve Mycobacterium tuberculosis identification in patients with pulmonary tuberculosis
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DOI: 10.1007/s10354-021-00871-5
Abstract: This study assessed the effectiveness and diagnostic significance of hypertonic saline sputum induction for improving Mycobacterium tuberculosis (MTB) detection. A prospective, randomized, open, two-arm, comparative study on MTB identification effectiveness when using inhaled sodium chloride… read more here.
Keywords: hypertonic saline; sputum; group; tuberculosis ... See more keywords
Bronchobiliary Fistula
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DOI: 10.1007/s11739-020-02572-0
Abstract: A 64-year-old woman presented with a 5-day duration of fever, jaundice, and productive cough of green colored sputum. She had undergone more than 20 sessions of endoscopic removal of recurrent choledocholithiasis, a cholecystectomy for cholelithiasis,… read more here.
Keywords: biliary tract; bilioptysis; sputum; bronchobiliary fistula ... See more keywords
Are saliva and deep throat sputum as reliable as common respiratory specimens for SARS-CoV-2 detection? A systematic review and meta-analysis
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DOI: 10.1016/j.ajic.2021.03.008
Abstract: Objective The COVID-19 pandemic raises an urgent need for large-scale control through easier, cheaper, and safer diagnostic specimens, including saliva and sputum. We aimed to conduct a systemic review and meta-analysis on the reliability and… read more here.
Keywords: review meta; sputum; analysis; sensitivity ... See more keywords
Cystic Fibrosis Sputum Rheology Correlates With Both Acute and Longitudinal Changes in Lung Function
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DOI: 10.1016/j.chest.2018.03.005
Abstract: Background Cystic fibrosis (CF) airway secretions are abnormal, contributing to decreased clearance and a cycle of infection and inflammation. CF sputum properties may predict disease progression. We hypothesized that sputum viscoelasticity and clearance abnormalities would… read more here.
Keywords: sputum; cystic fibrosis; rheology; lung function ... See more keywords
IMPACT OF MAIL-IN SPUTUM CULTURES IN DELIVERY OF CYSTIC FIBROSIS CARE VIA TELEHEALTH
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DOI: 10.1016/j.chest.2021.07.1308
Abstract: TOPIC: Education, Research, and Quality Improvement TYPE: Original Investigations PURPOSE: Cystic fibrosis (CF) is a multi-organ disease due to a mutation in the cystic fibrosis transmembrane conductance regulator gene. The mutation causes viscous mucus to… read more here.
Keywords: sputum; mail sputum; web response; mail ... See more keywords
The role of non‐invasive modalities for assessing inflammation in patients with non‐cystic fibrosis bronchiectasis
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DOI: 10.1016/j.cyto.2017.08.005
Abstract: Introduction Bronchiectasis is a heterogeneous entity, taking into account clinical characteristics, inflammatory response, effectiveness of treatment and frequency of exacerbations. In stable state non‐cystic fibrosis (non‐CF) bronchiectasis, little is known about non‐invasive techniques used for… read more here.
Keywords: non cystic; cystic fibrosis; bronchiectasis; sputum ... See more keywords
Proteome analysis of non-small cell lung cancer cell line secretomes and patient sputum reveals biofluid biomarker candidates for cisplatin response prediction.
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DOI: 10.1016/j.jprot.2019.01.018
Abstract: Molecular markers are urgently needed to select non-small cell lung cancer (NSCLC) patients most likely to benefit from platinum-based chemotherapies. Of particular interest are proteins that can be found in biofluids like sputum for non-invasive… read more here.
Keywords: sputum; biomarker candidates; cell; lung cancer ... See more keywords
Improved method for collection of sputum for tuberculosis testing to ensure adequate sample volumes for molecular diagnostic testing.
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DOI: 10.1016/j.mimet.2017.01.011
Abstract: The quality and quantity of sputum collected has an important impact on the laboratory diagnosis of pulmonary TB. We conducted a pilot study to assess a new collection cups for the collection of sputum for… read more here.
Keywords: method collection; sputum; improved method; tuberculosis ... See more keywords
Revival of an ancient Greek art: scent detection as diagnostic tool for tuberculosis
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DOI: 10.1038/s41390-018-0015-y
Abstract: In 2015, the World Health Organization (WHO) included a health target in the newly adopted Sustainable Development Goals, striving to end the tuberculosis (TB) epidemic by the year 2030. In low-income countries, TB continues to… read more here.
Keywords: detection; vocs derived; microscopy; sputum ... See more keywords