Pharmacokinetic/pharmacodynamic analysis of high‐dose tigecycline, by Monte Carlo simulation, in plasma and sputum of patients with hospital‐acquired pneumonia
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Pharmacy and Therapeutics"
DOI: 10.1111/jcpt.13823
Abstract: To Investigate the pharmacokinetic/pharmacodynamic (PK/PD) parameters of high‐dose tigecycline in plasma and sputum of patients with hospital‐acquired pneumonia (HAP), and provide a therapeutic regimen of multidrug‐resistant bacteria (MDRB) infections. read more here.
Keywords: plasma sputum; sputum patients; pharmacokinetic pharmacodynamic; patients hospital ... See more keywords
Oxygen consumption by polymorphonuclear leukocytes in sputum from patients with acute lower respiratory tract infection
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DOI: 10.1183/1393003.congress-2017.pa3320
Abstract: Restriction of oxygen (O2) is present in chronic lung infections with aggregated bacteria, but less is known about the physiological conditions during acute lower respiratory tract infections (LRTI). Polymorphonuclear leukocytes (PMNs) can deplete O2. Accumulation… read more here.
Keywords: lower respiratory; polymorphonuclear leukocytes; respiratory tract; acute lower ... See more keywords