Articles with "spy002" as a keyword



P911 Development and Characterization of SPY002, a Novel Extended Half-life Monoclonal Antibody Drug Candidate Targeting TL1A for the Treatment of IBD

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Published in 2024 at "Journal of Crohn's and Colitis"

DOI: 10.1093/ecco-jcc/jjad212.1041

Abstract: Tumor necrosis factor (TNF)-like ligand 1A (TL1A) mediates a broad spectrum of pro-inflammatory and fibrotic effects and is implicated in the pathogenesis of several immunologic disorders. Blockade of the interaction of TL1A with its cognate… read more here.

Keywords: extended half; tl1a; spy002; spy002 novel ... See more keywords