Fiber manipulation and post-assembly nanobody conjugation for adenoviral vector retargeting through SpyTag-SpyCatcher protein ligation
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DOI: 10.3389/fmolb.2022.1039324
Abstract: For adenoviruses (Ads) to be optimally effective in cancer theranostics, they need to be retargeted toward target cells and lose their natural tropism. Typically, this is accomplished by either engineering fiber proteins and/or employing bispecific… read more here.
Keywords: fiber; spycatcher; spytag spycatcher; nanobody ... See more keywords