Synthesis and Testing of Analogs of the Tuberculosis Drug Candidate SQ109 against Bacteria and Protozoa: Identification of Lead Compounds against Mycobacterium abscessus and Malaria Parasites.
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DOI: 10.1021/acsinfecdis.2c00537
Abstract: SQ109 is a tuberculosis drug candidate that has high potency against Mycobacterium tuberculosis and is thought to function at least in part by blocking cell wall biosynthesis by inhibiting the MmpL3 transporter. It also has… read more here.
Keywords: tuberculosis; drug candidate; sq109 bacteria; activity ... See more keywords