p62/SQSTM1 Fuels Melanoma Progression by Opposing mRNA Decay of a Selective Set of Pro-metastatic Factors.
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DOI: 10.1016/j.ccell.2018.11.008
Abstract: Modulators of mRNA stability are not well understood in melanoma, an aggressive tumor with complex changes in the transcriptome. Here we report the ability of p62/SQSTM1 to extend mRNA half-life of a spectrum of pro-metastatic… read more here.
Keywords: metastatic factors; p62 sqstm1; sqstm1 fuels; pro metastatic ... See more keywords