Improved squalene production through increasing lipid contents in Saccharomyces cerevisiae
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.26595
Abstract: Squalene, a valuable acyclic triterpene, can be used as a chemical commodity for pharmacology, flavor, and biofuel industries. Microbial production of squalene has been of great interest due to its limited availability, and increasing prices… read more here.
Keywords: squalene production; saccharomyces cerevisiae; production; squalene ... See more keywords
A rapid in‐house validated GC‐FID method for simultaneous determination of lipophilic bioactives in olive oil: Squalene, α‐tocopherol, and β‐sitosterol
Sign Up to like & getrecommendations! Published in 2017 at "European Journal of Lipid Science and Technology"
DOI: 10.1002/ejlt.201500420
Abstract: The analytical methodologies utilizing HPLC or GC techniques for the determination of predominant lipophilic bioactives in olive oil (β-sitosterol, squalene, and α-tocopherol) may include a number of sample pre-treatment steps (such as clean up (using… read more here.
Keywords: method; sitosterol; squalene; house ... See more keywords
Towards a Sustainable Route for the Production of Squalene Using Cyanobacteria
Sign Up to like & getrecommendations! Published in 2019 at "Waste and Biomass Valorization"
DOI: 10.1007/s12649-017-0191-8
Abstract: Treatment of slaughterhouse wastewater is a huge industrial problem. The use of an algae biorefinery platform could be a sustainable technological alternative that produces value-added compounds instead of dumping the wastewater. For this reason, this… read more here.
Keywords: production squalene; production; sustainable route; towards sustainable ... See more keywords
1H NMR combined with PLS for the rapid determination of squalene and sterols in vegetable oils.
Sign Up to like & getrecommendations! Published in 2019 at "Food chemistry"
DOI: 10.1016/j.foodchem.2019.02.072
Abstract: Proton nuclear magnetic resonance (1H NMR) combined with partial least squares (PLS) was developed for the rapid determination of squalene and sterols (brassicasterol, campesterol, stigmasterol and β-sitosterol) in 119 vegetable oils from 7 different species.… read more here.
Keywords: determination squalene; squalene sterols; nmr combined; vegetable oils ... See more keywords
Binary blend of maltodextrin and whey protein outperforms gum Arabic as superior wall material for squalene encapsulation
Sign Up to like & getrecommendations! Published in 2021 at "Food Hydrocolloids"
DOI: 10.1016/j.foodhyd.2021.106976
Abstract: Abstract The efficiency of high dextrose equivalent (DE) maltodextrin – whey protein isolate blend (MD-WPI) to perform as a delivery system for encapsulating squalene, a marine nutraceutical, was investigated by keeping gum Arabic (GA) as… read more here.
Keywords: maltodextrin whey; whey protein; squalene; gum arabic ... See more keywords
Chitosan - Whey protein as efficient delivery system for squalene: Characterization and functional food application.
Sign Up to like & getrecommendations! Published in 2019 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2019.05.153
Abstract: Squalene, a triterpenoid compound possessing excellent bioactivities, is not being utilized as a functional food ingredient due to its high susceptibility to oxidation. In the present study, the feasibility of chitosan-whey protein as an efficient… read more here.
Keywords: functional food; protein efficient; whey protein; chitosan whey ... See more keywords
Squalene containing solid lipid nanoparticles, a promising adjuvant system for yeast vaccines.
Sign Up to like & getrecommendations! Published in 2018 at "Vaccine"
DOI: 10.1016/j.vaccine.2018.03.019
Abstract: Potent adjuvant systems are required for subunit and single antigen based vaccines to provide sufficient immunogenicity. Furthermore, adjuvants can reduce the required number of immunisations and the antigen amount. Squalene nanoemulsions, like MF59® and AddaVax™,… read more here.
Keywords: containing solid; squalene containing; lipid nanoparticles; vaccine ... See more keywords
The yeast peroxisome: A dynamic storage depot and subcellular factory for squalene overproduction.
Sign Up to like & getrecommendations! Published in 2019 at "Metabolic engineering"
DOI: 10.1016/j.ymben.2019.11.001
Abstract: Engineering microbes to produce terpenes from renewable feedstock is a promising alternative to traditional production approaches. Generally, terpenes are not readily secreted by microbial cells, and their distribution within cells is usually obscure and often… read more here.
Keywords: overproduction; storage; engineering; subcellular factory ... See more keywords
Genome-Wide Association Study for Squalene Contents and Functional Haplotype Analysis in Rice
Sign Up to like & getrecommendations! Published in 2019 at "ACS Omega"
DOI: 10.1021/acsomega.9b02754
Abstract: Squalene is an isoprenoid compound that acts as the intermediate metabolite in cholesterol synthesis. Squalene is not very susceptible to peroxidation, and it quenches singlet oxygen in the skin, which is caused by UV exposure… read more here.
Keywords: genome wide; rice; study squalene; squalene ... See more keywords
A key mammalian cholesterol synthesis enzyme, squalene monooxygenase, is allosterically stabilized by its substrate
Sign Up to like & getrecommendations! Published in 2020 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1915923117
Abstract: Significance Cholesterol is an essential component of cell membranes and a precursor for steroid hormones and bile acids. Squalene monooxygenase (SM) is a rate-limiting enzyme in the cholesterol biosynthetic pathway and has been demonstrated to… read more here.
Keywords: cholesterol synthesis; squalene monooxygenase; cholesterol; squalene ... See more keywords
Optimisation of Microwave-Assisted Extraction of Squalene from Amaranthus spp. Seeds
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Microwave Power and Electromagnetic Energy"
DOI: 10.1080/08327823.2019.1677429
Abstract: Abstract Squalene is a triterpene of pharmaceutical interest, due to its antioxidant and anticancer properties. Amaranth oil is a source of plant origin with high squalene content which is extracted by conventional methods that involve… read more here.
Keywords: extraction; time; microwave assisted; assisted extraction ... See more keywords