Development of Squalene-Based Oil-in-Water Emulsion Adjuvants Using a Self-Emulsifying Drug Delivery System for Enhanced Antigen-Specific Antibody Titers
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s379950
Abstract: Introduction A recombinant protein cannot induce sufficient immune response by itself. Various substances, including cytokine and mineral, have been used as adjuvants to enhance the immunogenicity and efficacy of vaccines; however, most of them induce… read more here.
Keywords: squalene based; oil; based oil; oil water ... See more keywords
Formulation of an ovarian cancer vaccine with the squalene-based AddaVax adjuvant inhibits the growth of murine epithelial ovarian carcinomas
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Vaccine Research"
DOI: 10.7774/cevr.2022.11.2.163
Abstract: Purpose Epithelial ovarian carcinoma (EOC) is the most lethal of all human gynecologic malignancies. We previously reported that vaccination of female mice with the extracellular domain of anti-Müllerian hormone receptor II (AMHR2-ED) in complete Freund’s… read more here.
Keywords: cancer vaccine; epithelial ovarian; squalene based; ovarian cancer ... See more keywords