p21CIP1 controls the squamous differentiation response to replication stress
Sign Up to like & getrecommendations! Published in 2020 at "Oncogene"
DOI: 10.1038/s41388-020-01520-8
Abstract: The control of cell fate is critical to homeostasis and cancer. Cell cycle cdk inhibitor p21CIP1 has a central and paradoxical role in the regulatory crossroads leading to senescence, apoptosis, or differentiation. p21 is an… read more here.
Keywords: stress; differentiation; squamous differentiation; differentiation response ... See more keywords
FOXP4 inhibits squamous differentiation of atypical cells in cervical intraepithelial neoplasia via an ELF3‐dependent pathway
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Science"
DOI: 10.1111/cas.15489
Abstract: Although the human papillomavirus (HPV) vaccine is effective for preventing cervical cancers, this vaccine does not eliminate pre‐existing infections, and alternative strategies have been warranted. Here, we report that FOXP4 is a new target molecule… read more here.
Keywords: via elf3; elf3 dependent; squamous differentiation; differentiation ... See more keywords
Human Airway Basal Cells Undergo Reversible Squamous Differentiation and Reshape Innate Immunity.
Sign Up to like & getrecommendations! Published in 2023 at "American journal of respiratory cell and molecular biology"
DOI: 10.1165/rcmb.2022-0299oc
Abstract: Histological and lineage immunofluorescence examination herein revealed that healthy conducting airways of humans and animals harbor sporadic poorly differentiated epithelial patches mostly in the dorsal non-cartilage regions that remarkably manifest squamous differentiation. In vitro analysis… read more here.
Keywords: basal cells; airway basal; reversible squamous; squamous differentiation ... See more keywords
Squamous Differentiation in the Thyroid: Metaplasia, Neoplasia, or Bystander?
Sign Up to like & getrecommendations! Published in 2021 at "International journal of surgical pathology"
DOI: 10.1177/10668969211065126
Abstract: Background. Squamous differentiation within the thyroid is seen in a variety of settings. Squamous epithelium is non-native to the thyroid, and its debated origins span reactive metaplasia and developmental/embryologic remnants. Despite a lack of clarity… read more here.
Keywords: squamous differentiation; metaplasia; thyroid; squamous epithelium ... See more keywords
Primary ovarian serous carcinomas with extensive squamous differentiation: a case report and literature review
Sign Up to like & getrecommendations! Published in 2021 at "BMC Women's Health"
DOI: 10.1186/s12905-021-01336-y
Abstract: Background Primary ovarian serous carcinomas (OSC) with extensive squamous differentiation is a rare, and histological diagnostic criteria and biological behavior have not been fully established. We present an extremely rare case of primary OSC of… read more here.
Keywords: extensive squamous; ovarian serous; case; differentiation ... See more keywords
Prognostic impact of percentage of squamous differentiation in patients with nonbilharzial squamous cell carcinoma and transitional cell carcinoma treated with radical cystectomy.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2018.36.6_suppl.498
Abstract: 498Background: Squamous differentiation has been reported to occur in 10-22 % of transitional cell carcinoma. The prognostic impact of squamous differentiation is controversial. In addition, it remains unclear whether the percentage of squamous differentiation impact… read more here.
Keywords: squamous differentiation; cell carcinoma; cell; transitional cell ... See more keywords
The impact of Ki-67 index, squamous differentiation, and several clinicopathologic parameters on the recurrence of low and intermediate-risk endometrial cancer
Sign Up to like & getrecommendations! Published in 2021 at "Bosnian Journal of Basic Medical Sciences"
DOI: 10.17305/bjbms.2020.5437
Abstract: Endometrial endometrioid carcinoma (EEC) represents approximately 75-80% of endometrial carcinoma cases. Three hundred and thirty-six patients with EEC followed-up in the authors’ medical center between 2010 and 2018 were included in our study. Two hundred… read more here.
Keywords: intermediate risk; squamous differentiation; index; low intermediate ... See more keywords