Structural-Guided Identification of Small Molecule Inhibitor of UHRF1 Methyltransferase Activity
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DOI: 10.3389/fgene.2022.928884
Abstract: Ubiquitin-like containing plant homeodomain Ring Finger 1 (UHRF1) protein is recognized as a cell-cycle-regulated multidomain protein. UHRF1 importantly manifests the maintenance of DNA methylation mediated by the interaction between its SRA (SET and RING associated)… read more here.
Keywords: methylation; chicoric acid; sra domain; inhibitor ... See more keywords