Assessment of Serum sRANKL, sRANKL/OPG Ratio, and Other Bone Turnover Markers with the Estimated 10-Year Risk of Major and Hip Osteoporotic Fractures in Rheumatoid Arthritis: A Cross-Sectional Study
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DOI: 10.1155/2021/5567666
Abstract: Background Fracture risk assessment tool (FRAX) index was developed for estimating of the 10-year risk of major or hip osteoporotic fracture. To date, there is insufficient information regarding the correlation between FRAX and serum bone… read more here.
Keywords: opg ratio; risk; hip; serum ... See more keywords
Decreased level of soluble receptor activator of nuclear factor-κβ ligand (sRANKL) in overweight and obese children
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DOI: 10.3389/fendo.2022.963467
Abstract: Introduction Childhood obesity contributes to the development of cardiovascular diseases. The molecular pathway – receptor activator of nuclear factor-κβ ligand (RANKL), its receptor RANK and osteoprotegerin (OPG) - takes part not only in bone metabolism… read more here.
Keywords: opg srankl; receptor activator; obese children; overweight obese ... See more keywords
Inhibition of Neddylation Suppresses Osteoclast Differentiation and Function In Vitro and Alleviates Osteoporosis In Vivo
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DOI: 10.3390/biomedicines10102355
Abstract: Neddylation, or the covalent addition of NEDD8 to specific lysine residue of proteins, is a reversible posttranslational modification, which regulates numerous biological functions; however, its involvement and therapeutic significance in osteoporosis remains unknown. Our results… read more here.
Keywords: osteoclast differentiation; neddylation; osteoporosis; factor ... See more keywords