CD55 is upregulated by cAMP/PKA/AKT and modulates human decidualization via Src and ERK pathway and decidualization‐related genes
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Reproduction and Development"
DOI: 10.1002/mrd.23569
Abstract: Decidualization is an essential process for embryo implantation and maintenance of pregnancy, and abnormal decidualization contributed to several pregnancy disorders like a miscarriage. The objective of this study was to explore the regulation and function… read more here.
Keywords: cd55; expression; decidualization; decidualization related ... See more keywords
Achieving minimal residual disease-negative by multiparameter flow cytometry may ameliorate a poor prognosis in MM patients with high-risk cytogenetics: a retrospective single-center analysis
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Hematology"
DOI: 10.1007/s00277-019-03609-x
Abstract: The aim of our study was to evaluate the prognostic impact of minimal residual disease (MRD) and high-risk cytogenetics (HRCs) on outcomes in multiple myeloma (MM) patients. We applied multiparameter flow cytometry (MFC) to detect… read more here.
Keywords: pfs; risk; minimal residual; mrd ... See more keywords
DBS is activated by EPHB2/SRC signaling-mediated tyrosine phosphorylation in HEK293 cells
Sign Up to like & getrecommendations! Published in 2019 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-019-03552-5
Abstract: It is well known that Rho family small GTPases (Rho GTPase) has a role of molecular switch in intracellular signal transduction. The switch cycle between GTP-bound and GDP-bound state of Rho GTPase regulates various cell… read more here.
Keywords: rho gtpase; dbs; ephb2 src; src ... See more keywords
Src mediates β-adrenergic receptor induced YAP tyrosine phosphorylation
Sign Up to like & getrecommendations! Published in 2020 at "Science China Life Sciences"
DOI: 10.1007/s11427-020-1652-9
Abstract: The Hippo pathway is a newly identified pathway and evolutionarily conserved from flies to humans mainly regulating cell proliferation. Transcriptional co-activator Yes-associated protein (YAP) functions as a major downstream effector and key node of the… read more here.
Keywords: tyrosine phosphorylation; src; adrenergic receptor; phosphorylation ... See more keywords
Association of Abdominal Aortic Aneurysm and Simple Renal Cysts: a Systematic Review and Meta-analysis.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of vascular surgery"
DOI: 10.1016/j.avsg.2021.01.075
Abstract: BACKGROUND-OBJECTIVE Prior studies have suggested a higher prevalence of simple renal cysts (SRC) among patients with aortic disease, including abdominal aortic aneurysms (AAA). Thus, the aim of this study was to systematically review all currently… read more here.
Keywords: analysis; patients aaa; src; simple renal ... See more keywords
Temperature sensitivities of metazoan and pre-metazoan Src kinases
Sign Up to like & getrecommendations! Published in 2020 at "Biochemistry and Biophysics Reports"
DOI: 10.1016/j.bbrep.2020.100775
Abstract: Homologous enzymes from different species display functional characteristics that correlate with the physiological and environmental temperatures encountered by the organisms. In this study, we have investigated the temperature sensitivity of the nonreceptor tyrosine kinase Src.… read more here.
Keywords: src kinases; kinases temperature; temperature; src ... See more keywords
Positive regulatory role of c-Src-mediated TRIM25 tyrosine phosphorylation on RIG-I ubiquitination and RIG-I-mediated antiviral signaling pathway.
Sign Up to like & getrecommendations! Published in 2018 at "Cellular immunology"
DOI: 10.1016/j.cellimm.2018.08.004
Abstract: Retinoic acid-inducible gene I (RIG-I) detects viral RNAs and induces antiviral responses. During viral RNA recognition by RIG-I, tripartite motif protein 25 (TRIM25) plays a critical regulatory role by inducing K63-linked RIG-I polyubiquitination. Previous proteomics… read more here.
Keywords: regulatory role; rig; tyrosine phosphorylation; src ... See more keywords
Inhibition of oncogenic Src induces FABP4-mediated lipolysis via PPARγ activation exerting cancer growth suppression
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.02.015
Abstract: Background c-Src is a driver oncogene well-known for tumorigenic signaling, but little for metabolic function. Previous reports about c-Src regulation of glucose metabolism prompted us to investigate its function in other nutrient modulation, particularly in… read more here.
Keywords: inhibition oncogenic; lipolysis; src; cancer ... See more keywords
Numerical study of fatigue behaviour of steel reinforced concrete (SRC) beams
Sign Up to like & getrecommendations! Published in 2017 at "Engineering Fracture Mechanics"
DOI: 10.1016/j.engfracmech.2017.02.017
Abstract: Abstract There is an increased use of steel reinforced concrete (SRC) beams in civil engineering construction where fatigue loading could be critical. Most of the research on SRC beams so far was focused on static… read more here.
Keywords: src beams; study; steel reinforced; src ... See more keywords
Endocrine disruptor chlorpyrifos promotes migration, invasion, and stemness phenotype in 3D cultures of breast cancer cells and induces a wide range of pathways involved in cancer progression.
Sign Up to like & getrecommendations! Published in 2021 at "Environmental research"
DOI: 10.1016/j.envres.2021.111989
Abstract: Organophosphorus chlorpyrifos (CPF) is currently considered an endocrine disruptor (ED), as it can imitate hormone actions both in vitro and in vivo. We recently reported that CPF induces migration and invasion in 2D cultures and… read more here.
Keywords: invasion; cpf increased; migration; src ... See more keywords
Airway Epithelial IL-33 Secretion and Feedback Signaling is Associated with Redox Activation of Src Kinase
Sign Up to like & getrecommendations! Published in 2017 at "Free Radical Biology and Medicine"
DOI: 10.1016/j.freeradbiomed.2017.10.319
Abstract: The airway epithelium forms the primary defense against inhaled allergens and environmental insults to the respiratory system. Aside from acting as a physical barrier, the epithelium also signals for reparative and inflammatory responses by generating… read more here.
Keywords: secretion; activation src; src; type ... See more keywords