Dauricine inhibits proliferation and promotes death of melanoma cells via inhibition of Src/STAT3 signaling
Sign Up to like & getrecommendations! Published in 2021 at "Phytotherapy Research"
DOI: 10.1002/ptr.7089
Abstract: Melanoma is the most common type of skin cancer. Signal transducer and activator of transcription 3 (STAT3) signaling has been demonstrated to be a therapeutic target for melanoma. Dauricine (Dau), an alkaloid compound isolated from… read more here.
Keywords: melanoma; melanoma cells; death melanoma; src stat3 ... See more keywords
Nigericin exerts anticancer effects through inhibition of the SRC/STAT3/BCL-2 in osteosarcoma.
Sign Up to like & getrecommendations! Published in 2022 at "Biochemical pharmacology"
DOI: 10.1016/j.bcp.2022.114938
Abstract: The treatment of osteosarcoma has reached a bottleneck period in recent 30 years, there is an urgent need to find new drugs and treatment methods. Nigericin, an antibiotic derived from Streptomyces hygroscopicus, has exerted promising… read more here.
Keywords: nigericin exerts; src stat3; osteosarcoma; stat3 ... See more keywords
The synergistic Reduning and cefmetazole sodium treatment of severe pneumonia is mediated by the AhR-Src-STAT3 pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of thoracic disease"
DOI: 10.21037/jtd-22-126
Abstract: Background Reduning (RDN) is a common Chinese medicine preparation with antibacterial, anti-inflammatory, antiviral and immunomodulatory effects in respiratory infectious diseases. Clinically, it is used in combination with antibiotics, but its synergistic effect and mechanism in… read more here.
Keywords: src stat3; expression; severe pneumonia; pneumonia ... See more keywords
Anti-Cancer Potential of Oxialis obtriangulata in Pancreatic Cancer Cell through Regulation of the ERK/Src/STAT3-Mediated Pathway
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DOI: 10.3390/molecules25102301
Abstract: As a plant medicine, Oxalidaceae has been used to treat various diseases in Korea. However, there is little data on the anti-cancer efficacy of Oxalidaceae, particularly O. obtriangulata. This study aimed to investigate the anti-cancer… read more here.
Keywords: ooe; src stat3; pancreatic cancer; cancer ... See more keywords