Polyamines and eIF5A hypusination facilitate SREBP2 synthesis and cholesterol production leading to enhanced enterovirus attachment and infection
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DOI: 10.1371/journal.ppat.1011317
Abstract: Metabolism is key to cellular processes that underlie the ability of a virus to productively infect. Polyamines are small metabolites vital for many host cell processes including proliferation, transcription, and translation. Polyamine depletion also inhibits… read more here.
Keywords: attachment; infection; srebp2 synthesis; synthesis ... See more keywords