Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-ҡB activators for the treatment of ALS.
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DOI: 10.1016/j.ejmech.2020.112952
Abstract: ALS is a rare type of progressive neurological disease with unknown etiology. It results in the gradual degeneration and death of motor neurons responsible for controlling the voluntary muscles. Identification of mutations in the superoxide… read more here.
Keywords: sri 22819; activity relationship; structure activity; sri ... See more keywords