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   Articles with "srna mrna" as a keyword



sInterBase: a comprehensive database of Escherichia coli sRNA–mRNA interactions

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recommendations! Published in 2023 at "Bioinformatics"

DOI: 10.1093/bioinformatics/btad172

Abstract: Abstract Summary sInterBase is a comprehensive and easy-to-operate web-based platform for mining experimentally identified sRNA–mRNA interactions in Escherichia coli. Interactions in the database are annotated with an interaction duplex and a set of descriptive features.… read more here.

Keywords: sinterbase comprehensive; escherichia coli; srna mrna; mrna interactions ... See more keywords

Hfq Globally Binds and Destabilizes sRNAs and mRNAs in Yersinia pestis

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recommendations! Published in 2019 at "mSystems"

DOI: 10.1128/msystems.00245-19

Abstract: Discovered in 1968 as an Escherichia coli host factor that was essential for replication of the bacteriophage Qβ, the Hfq protein is a ubiquitous and highly abundant RNA-binding protein in many bacteria. With the assistance… read more here.

Keywords: base pairing; yersinia pestis; hfq; srna mrna ... See more keywords

The functional small RNA interactome reveals targets for the vancomycin-responsive sRNA RsaOI in vancomycin-tolerant Staphylococcus aureus

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recommendations! Published in 2024 at "mSystems"

DOI: 10.1128/msystems.00971-23

Abstract: ABSTRACT Small RNAs have been found to control a broad range of bacterial phenotypes including tolerance to antibiotics. Vancomycin tolerance in multidrug resistance Staphylococcus aureus is correlated with dysregulation of small RNAs although their contribution… read more here.

Keywords: srna; treatment; cell wall; srna mrna ... See more keywords

GNNs and ensemble models enhance the prediction of new sRNA-mRNA interactions in unseen conditions

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recommendations! Published in 2025 at "BMC Bioinformatics"

DOI: 10.1186/s12859-025-06153-w

Abstract: Bacterial small RNAs (sRNAs) are pivotal in post-transcriptional regulation, affecting functions like virulence, metabolism, and gene expression by binding specific mRNA targets. Identifying these targets is crucial to understanding sRNA regulation across species. Despite advancements… read more here.

Keywords: unseen conditions; interactions unseen; srna mrna; ensemble models ... See more keywords