Reprograming of sRNA target specificity by the leader peptide peTrpL in response to antibiotic exposure
Sign Up to like & getrecommendations! Published in 2021 at "Nucleic Acids Research"
DOI: 10.1093/nar/gkab093
Abstract: Abstract Trans-acting regulatory RNAs have the capacity to base pair with more mRNAs than generally detected under defined conditions, raising the possibility that sRNA target specificities vary depending on the specific metabolic or environmental conditions.… read more here.
Keywords: srna target; rntrpl; target; peptide petrpl ... See more keywords
sRNA Target Prediction Organizing Tool (SPOT) Integrates Computational and Experimental Data To Facilitate Functional Characterization of Bacterial Small RNAs
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DOI: 10.1128/msphere.00561-18
Abstract: Small RNAs (sRNAs) regulate gene expression in diverse bacteria by interacting with mRNAs to change their structure, stability, or translation. Hundreds of sRNAs have been identified in bacteria, but characterization of their regulatory functions is… read more here.
Keywords: characterization; target prediction; srna target; spot ... See more keywords
The impact of various seed, accessibility and interaction constraints on sRNA target prediction- a systematic assessment
Sign Up to like & getrecommendations! Published in 2020 at "BMC Bioinformatics"
DOI: 10.1186/s12859-019-3143-4
Abstract: Background Seed and accessibility constraints are core features to enable highly accurate sRNA target screens based on RNA-RNA interaction prediction. Currently, available tools provide different (sets of) constraints and default parameter sets. Thus, it is… read more here.
Keywords: seed; srna target; target prediction; accessibility ... See more keywords