Hydrophobicity, rather than secondary structure, is essential for the SRP dependent targeting of GPR35 to the ER membrane
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DOI: 10.1007/s10863-019-9785-0
Abstract: The folding and targeting of hydrophobic transmembrane domains poses a major challenge to the cell. Several membrane proteins have been shown to gain some degree of secondary structure within the ribosome tunnel and to retain… read more here.
Keywords: secondary structure; srp dependent; structure; hydrophobicity ... See more keywords