Mechanism of Signal Sequence Handover From NAC To SRP on Ribosomes During ER-protein Targeting
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DOI: 10.1126/science.abl6459
Abstract: The nascent polypeptide–associated complex (NAC) interacts with newly synthesized proteins at the ribosomal tunnel exit and competes with the signal recognition particle (SRP) to prevent mistargeting of cytosolic and mitochondrial polypeptides to the endoplasmic reticulum… read more here.
Keywords: srp; nac; srp ribosomes; nascent polypeptide ... See more keywords