Articles with "srp72" as a keyword



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Human apo-SRP72 and SRP68/72 complex structures reveal the molecular basis of protein translocation

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Published in 2017 at "Journal of Molecular Cell Biology"

DOI: 10.1093/jmcb/mjx010

Abstract: Abstract The co-translational targeting or insertion of secretory and membrane proteins into the endoplasmic reticulum (ER) is a key biological process mediated by the signal recognition particle (SRP). In eukaryotes, the SRP68–SRP72 (SRP68/72) heterodimer plays… read more here.

Keywords: srp68; srp72 srp68; srp72; apo srp72 ... See more keywords
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Mutations in Genes Associated with Familial Predisposition to Myeloid Neoplasms: Their Frequency and Associations with Pretreatment Characteristics in Adult Patients (Pts) with Presumably Sporadic De Novo Acute Myeloid Leukemia (AML)

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Published in 2018 at "Blood"

DOI: 10.1182/blood-2018-99-120085

Abstract: The effects of germline variants in the development of myeloid neoplasms, including AML, were largely neglected for decades. However, several myeloid neoplasms with germline predisposition have been recently recognized as separate entities in the 2016… read more here.

Keywords: myeloid neoplasms; srp72; frequency; myeloid ... See more keywords