Splicing factor SRSF3 promotes the progression of cervical cancer through regulating DDX5
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Carcinogenesis"
DOI: 10.1002/mc.23477
Abstract: Aberrant alternative splicing (AS) profoundly affects tumorigenesis and cancer progression. Serine/arginine‐rich splicing factor 3 (SRSF3) regulates the AS of precursor mRNAs and acts as a proto‐oncogene in many tumors, but its function and potential mechanisms… read more here.
Keywords: cervical cancer; ddx5; srsf3; factor srsf3 ... See more keywords
SRSF3 functions as an oncogene in colorectal cancer by regulating the expression of ArhGAP30
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Cell International"
DOI: 10.1186/s12935-020-01201-2
Abstract: Background Splicing factor SRSF3 is an oncogene and overexpressed in various kinds of cancers, however, the function and mechanism involved in colorectal cancer (CRC) remained unclear. The aim of this study was to explore the… read more here.
Keywords: srsf3; colorectal cancer; expression; crc ... See more keywords
Long Non-coding RNA T-uc.189 Modulates Neural Progenitor Cell Fate by Regulating Srsf3 During Mouse Cerebral Cortex Development
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2021.709684
Abstract: Neurogenesis is a complex process that depends on the delicate regulation of spatial and temporal gene expression. In our previous study, we found that transcribed ultra-conserved regions (T-UCRs), a class of long non-coding RNAs that… read more here.
Keywords: srsf3; rna 189; long non; non coding ... See more keywords
SRSF3 Expression Serves as a Potential Biomarker for Prognostic and Immune Response in Pan-Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.808530
Abstract: Serine-rich splicing factor3 (SRSF3) plays an essential role in cell proliferation and inducing and maintaining of cancers as a proto-oncogene. However, the mechanisms of SRSF3 in pan-cancers are still unknown. In our study, a visualized… read more here.
Keywords: srsf3; pan cancer; srsf3 expression; expression ... See more keywords
SRSF3 Promotes Angiogenesis in Colorectal Cancer by Splicing SRF
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.810610
Abstract: SRSF3, an important member of the serine/arginine-rich protein (SRp) family, is highly expressed in various tumors and plays an important role in tumor cell proliferation, migration and invasion. However, it is still unclear whether SRSF3… read more here.
Keywords: srf; srsf3; crc; colorectal cancer ... See more keywords
Cooperative Binding of SRSF3 to Structured 3’ss-α Exon RNA during α Exon Inclusion in the ZO-1 mRNA
Sign Up to like & getrecommendations! Published in 2023 at "Current Issues in Molecular Biology"
DOI: 10.3390/cimb45010039
Abstract: ZO-1α+ and ZO-1α− proteins are expressed in hermetic and leaky tight junctions, respectively. Two cis-acting distant exonic elements partly activate the 240 nucleotide-long α exon producing the ZO-1α+ isoform. However, the elements within and around… read more here.
Keywords: rna; srsf3; binding srsf3; cooperative binding ... See more keywords
SRSF3 promotes pluripotency through Nanog mRNA export and coordination of the pluripotency gene expression program
Sign Up to like & getrecommendations! Published in 2018 at "eLife"
DOI: 10.7554/elife.37419
Abstract: The establishment and maintenance of pluripotency depend on precise coordination of gene expression. We establish serine-arginine-rich splicing factor 3 (SRSF3) as an essential regulator of RNAs encoding key components of the mouse pluripotency circuitry, SRSF3… read more here.
Keywords: pluripotency; nanog mrna; gene expression; srsf3 ... See more keywords