SRSF5‐Mediated Alternative Splicing of M Gene is Essential for Influenza A Virus Replication: A Host‐Directed Target Against Influenza Virus
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DOI: 10.1002/advs.202203088
Abstract: Splicing of influenza A virus (IAV) RNA is an essential process in the viral life cycle that involves the co‐opting of host factors. Here, it is demonstrated that induction of host serine and arginine‐rich splicing… read more here.
Keywords: replication; srsf5; host; virus ... See more keywords
Mutually exclusive acetylation and ubiquitylation of the splicing factor SRSF5 control tumor growth
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DOI: 10.1038/s41467-018-04815-3
Abstract: Most tumor cells take up more glucose than normal cells. Splicing dysregulation is one of the molecular hallmarks of cancer. However, the role of splicing factor in glucose metabolism and tumor development remains poorly defined.… read more here.
Keywords: tumor growth; splicing factor; srsf5; tumor ... See more keywords
SRSF5 Regulates the Expression of BQ323636.1 to Modulate Tamoxifen Resistance in ER-Positive Breast Cancer
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DOI: 10.3390/cancers15082271
Abstract: Simple Summary Overexpression of BQ can confer tamoxifen resistance in ER +ve breast cancer. BQ is a variant of NCOR2 spliced through the exclusion of exon 11. SRSF5 is found to be involved in regulating… read more here.
Keywords: tam resistance; expression; breast cancer; resistance ... See more keywords