Gadd45g is required for timely Sry expression independently of RSPO1 activity.
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DOI: 10.1530/rep-21-0443
Abstract: Sex determination in mammals is controlled by the dominance of either pro-testis (SRY-SOX9-FGF9) or pro-ovary (RSPO1-WNT4-FOXL2) genetic pathways during early gonad development in XY and XX embryos, respectively. We have previously shown that early, robust… read more here.
Keywords: expression; sry expression; sex reversal; gadd45g ... See more keywords