Idiopathic and Systemic Sclerosis‐Associated Pulmonary Arterial Hypertension: A Comparison of Demographic, Hemodynamic, and MRI Characteristics and Outcomes
Sign Up to like & getrecommendations! Published in 2017 at "Chest"
DOI: 10.1016/j.chest.2017.02.010
Abstract: Background Previous studies have identified survival in systemic sclerosis (SSc)‐associated pulmonary arterial hypertension (SSc‐PAH) as being worse than in idiopathic pulmonary arterial hypertension (IPAH). We investigated differences between these conditions by comparing demographic, hemodynamic, and… read more here.
Keywords: pulmonary arterial; arterial hypertension; ssc pah;
The effects of oral treatment for systemic sclerosis related pulmonary arterial hypertension: A systematic review and meta-analysis
Sign Up to like & getrecommendations! Published in 2019 at "Modern Rheumatology"
DOI: 10.1080/14397595.2019.1704125
Abstract: Abstract Objectives The usage of oral therapies, endothelin receptor antagonists (ERAs), phosphodiesterase type-5 (PDE-5) inhibitors and prostaglandin analogs has resulted in improved outcomes in patients with pulmonary arterial hypertension related to systemic sclerosis (SSc-PAH). However,… read more here.
Keywords: arterial hypertension; analysis; treatment; pulmonary arterial ... See more keywords
Biomarkers of haemodynamic severity of systemic sclerosis-associated pulmonary arterial hypertension by serum proteome analysis
Sign Up to like & getrecommendations! Published in 2022 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/ard-2022-223237
Abstract: Objectives To mine the serum proteome of patients with systemic sclerosis-associated pulmonary arterial hypertension (SSc-PAH) and to detect biomarkers that may assist in earlier and more effective diagnosis and treatment. Methods Patients with limited cutaneous… read more here.
Keywords: systemic sclerosis; sclerosis associated; serum proteome; ssc pah ... See more keywords
Trends in systemic sclerosis and systemic sclerosis-related pulmonary arterial hypertension mortality in the USA
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DOI: 10.1183/23120541.00309-2019
Abstract: There are limited data nationwide on the burden of systemic sclerosis (SSc)-related mortality. We aimed to determine recent trends in SSc and SSc-related pulmonary arterial hypertension (PAH) mortality overall and across population subgroups. Using death… read more here.
Keywords: ssc pah; pah; systemic sclerosis; mortality ... See more keywords
Systemic sclerosis-associated pulmonary arterial hypertension in children.
Sign Up to like & getrecommendations! Published in 2021 at "Cardiovascular diagnosis and therapy"
DOI: 10.21037/cdt-20-901
Abstract: Systemic sclerosis (SSc) is a rare disease in childhood and is characterized by a combination of vasculopathy, inflammation, autoimmunity, and fibrogenesis with individually varying expression pattern. Pulmonary arterial hypertension (PAH) is a serious complication of… read more here.
Keywords: pah; pulmonary arterial; disease; systemic sclerosis ... See more keywords
Identification and Validation of Key Genes Associated With Systemic Sclerosis-Related Pulmonary Hypertension
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2020.00816
Abstract: Systemic sclerosis-associated with pulmonary arterial hypertension (SSc-PAH) is still a major cause of SSc related deaths. Early diagnosis and prompt treatment are crucial to reduce the mortality of patients with SSc-PAH. To screen the candidate… read more here.
Keywords: ssc pah; key genes; systemic sclerosis; validation ... See more keywords
Altered Cellular Immunity and Differentially Expressed Immune-Related Genes in Patients With Systemic Sclerosis–Associated Pulmonary Arterial Hypertension
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.868983
Abstract: Systemic sclerosis (SSc) is the most common connective tissue disease causing pulmonary hypertension (PAH). However, the cause and potential immune molecular events associated with PAH are still unclear. Therefore, it is particularly essential to analyze… read more here.
Keywords: immune related; ssc pah; ssc; hdac1 ... See more keywords
Biomarkers for Pulmonary Vascular Remodeling in Systemic Sclerosis: A Pathophysiological Approach
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2018.00587
Abstract: Pulmonary arterial hypertension (PAH) is a severe complication of systemic sclerosis (SSc) associated with high morbidity and mortality. There are several biomarkers of SSc-PAH, reflecting endothelial physiology, inflammation, immune activation, extracellular matrix, metabolic changes, or… read more here.
Keywords: ssc pah; pah; physiology; systemic sclerosis ... See more keywords
MiRNAs in Systemic Sclerosis Patients with Pulmonary Arterial Hypertension: Markers and Effectors
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DOI: 10.3390/biomedicines10030629
Abstract: Background: Pulmonary arterial hypertension (PAH) is a major cause of death in systemic sclerosis (SSc). Early detection may improve patient outcomes. Methods: We searched for circulating miRNAs that would constitute biomarkers in SSc patients with… read more here.
Keywords: mir let; ssc pah; pulmonary arterial; pah ... See more keywords