FRI0404 Characterisation of a monocytes/macrophages cell subset co-expressing both m1 and m2 phenotype markers in systemic sclerosis patients
Sign Up to like & getrecommendations! Published in 2018 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2018-eular.6225
Abstract: Background In the pathogenesis of systemic sclerosis (SSc), the immune cell activation is an important event that includes alteration in the macrophage polarisation.1 Macrophages may polarise into classically activated (M1), which are characterised by the… read more here.
Keywords: monocytes macrophages; cd206; phenotype markers; cd163 cd206 ... See more keywords
THU0348 IDENTIFICATION OF CIRCULATING CELLS WITH AN HYBRID M1/M2 MACROPHAGE PHENOTYPE IN SYSTEMIC SCLEROSIS PATIENTS AND CORRELATIONS WITH SELECTED CLINICAL ASPECTS
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.6748
Abstract: Background: Systemic sclerosis (SSc) is characterized by immune system alterations, vascular damage and fibrosis (1). Macrophages seem to have an emerging role in SSc, and the characterization of their polarized phenotype, starting from the dichotomic… read more here.
Keywords: circulating cells; clinical aspects; systemic sclerosis; percentage ... See more keywords
SAT0300 SERUM FROM “EARLY” SYSTEMIC SCLEROSIS PATIENTS ALREADY INDUCES THE ALTERNATIVELY ACTIVATED MACROPHAGE PHENOTYPE (M2) IN CULTURED HUMAN MONOCYTES
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DOI: 10.1136/annrheumdis-2020-eular.4552
Abstract: Alternatively activated (M2) macrophages seem to play a role in the fibrotic process of systemic sclerosis (SSc) as potential inducers of tissue fibrosis through their secretion of specific cytokines and chemokines, such as interleukin-10 (IL-10),… read more here.
Keywords: macrophage; nvc; none declared; ssc pts ... See more keywords