SSIPe: accurately estimating protein-protein binding affinity change upon mutations using evolutionary profiles in combination with an optimized physical energy function
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DOI: 10.1093/bioinformatics/btz926
Abstract: MOTIVATION Most proteins perform their biological functions through interactions with other proteins in cells. Amino acid mutations, especially those occurring at protein interfaces, can change the stability of protein-protein interactions (PPIs) and impact their functions,… read more here.
Keywords: protein; ssipe; protein protein; energy function ... See more keywords